ABSTRACT
Objective To explore the effects of ziprasidone combined with psychological intervention on drug related adverse reactions in the treatment of schizophrenia. Methods 62 patients with schizophrenia collected in Shaoxing seventh people's hospital from January 2016 to January 2017 were divided into study group (n=31) and control group (n=31) by single and double digital methods. The control group were received ziprasidone, the study group were received ziprasidone combined with psychological intervention. PANSS score and drug related adverse reactions in the two groups were recorded. Results Before treatment, PANSS score in the two groups has no statistical difference. PANSS score in the study group were decreased significantly than that in the control group (P<0.05). Insomnia or sleepiness, gastrointestinal reactions, headache, dizziness and other drug related adverse reactions in the study goup were significantly lower than those in the control group (P<0.05). Conclusion In schizophrenia treatment, ziprasidone combined with psychological intervention can effectively improve the therapeutic effect on the basis of reducing drug-related adverse reactions.
ABSTRACT
Objective To explore the effects of ziprasidone combined with psychological intervention on drug related adverse reactions in the treatment of schizophrenia. Methods 62 patients with schizophrenia collected in Shaoxing seventh people's hospital from January 2016 to January 2017 were divided into study group (n=31) and control group (n=31) by single and double digital methods. The control group were received ziprasidone, the study group were received ziprasidone combined with psychological intervention. PANSS score and drug related adverse reactions in the two groups were recorded. Results Before treatment, PANSS score in the two groups has no statistical difference. PANSS score in the study group were decreased significantly than that in the control group (P<0.05). Insomnia or sleepiness, gastrointestinal reactions, headache, dizziness and other drug related adverse reactions in the study goup were significantly lower than those in the control group (P<0.05). Conclusion In schizophrenia treatment, ziprasidone combined with psychological intervention can effectively improve the therapeutic effect on the basis of reducing drug-related adverse reactions.